Retinoic acid in immunity and inflammation.

We have recently identified a role for the transcriptional repressor HIC1 as a retinoic acid-dependent regulator of T cell function in the gut. We are looking at how HIC1 integrates retinoic acid signals to control T cell-dependent immunity and inflammation. Very excited about this- will update soon.

Here is my submitted NHMRC grant application that outlines the studies we are undertaking on HIC1 in T cells.